Research Directions

Pathophysiology of the skin barrier

Skin photoaging and itchy skin

Inflammatory skin diseases

Cardiac arrhythmia and heart failure

Retinopathy and age-related macular degeneration

Pharmacological and efficacy evaluation of natural ingredients

Cosmeceutics

Research Themes

Therapeutic potential and molecular mechanism of Chinese herbal medicine ingredients and their extracts on inflammatory skin diseases.

Treatment strategies and applications of Chinese herbal medicine ingredients and their extracts in allergic skin diseases.

Study on Anti-photoaging of Chinese herbal medicine ingredients and their extracts.

Study on anti-arrhythmia and heart failure of Chinese herbal medicine ingredients and their extracts.

Study on the anti-retinopathy of Chinese herbal medicine ingredients and their extracts.

Study on the application of carotenoid and flavonoid in skin barrier defect diseases.

Methods and Materials

HaCaT, Hs68, human keratinocyte and fibroblast, RBL-2H3, RPE, RF/6A, H9c2, HL-1, isolated single heart cells

Ultraviolet radiation (UVA, UVB, and UVC)

Allergen stimulation (including TNF-alpha, interferon-gamma, interleukin, chemokine, etc.)

Langendorff isolated heart preparation

Ischemic reperfusion model, cardiac electrophysiology

Intracellular calcium concentration detection

qPCR, Western blotting, ImageXpress®Micro Confocal High-Content Imaging System